Protein Labeling Reagents
Biotium CD63 (Late Endosomes Marker)(LAMP3/2789), Biotin conjugate, 0.1mg/mL
This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is stro
Biotium CD63 (Late Endosomes Marker) (rMX-49.129.5), Biotin conjugate, 0.1mg/mL
This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly
Echelon Biosciences Research Labs BIOTIN-PHOSPHATIDYLETHANOLAMIN
NC3245569 BIOTIN-PHOSPHATIDYLETHANOLAMIN
Sigma Aldrich Fine Chemicals Biosciences Biotin Protein Labeling Ki
for labeling of proteins with biotin.free amino acids of the protein to be labeled react with D-biotinoyl-epsilon-aminocaproic acid-N-hydroxy-succinimide ester (biotin-7-NHS) by forming a stable amino bond. Non reacted biotin-7-NHS is separated on a Sephadex G-25 column.
Cell Signaling Technology PathScanR Cleaved PARP Asp214 Sandwich ELISA Kit 50 Kit
PathScanR Cleaved PARP Asp214 Sandwich ELISA Kit 50 Kit
Biotium OX40 / CD134/ TNFRSF4 (Immuno-Oncology Target)(OX40/3108), Biotin conjugate, 0.1mg/mL
ThisMAb recognizes a protein of 43 kDa, identified as OX40, which is also known as CD134. OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand/TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid cells. OX40 is upregulated at the sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low a
Biotium CD63 (Late Endosomes Marker)(LAMP3/2789), Biotin conjugate, 0.1mg/mL
This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is stro
Cayman Chemical Alkynyl-bIotIn 10mg
A form of biotin with a terminal alkyne group separated by two polyethylene glycol moieties; used to add biotin to other molecules bearing an azide group using click chemistry
Sino Biological Recombinant Human ST2/IL-1 RL1 Protein (His Tag), Biotinylated, HPLC-verified 20 µg
A DNA sequence encoding the human IL1RL1 isoform 2 (NP_003847.2) (Met1-Phe328) was expressed fused with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro.
Cayman Chemical ANTIBODY o p-DDE 50mg
A metabolite and degradation product of the pesticide DDT; accumulates in various fish and sediment surrounding a DDT manufacturing plant; inhibits estrogen binding to rtERs (IC50 = 3.2 μM); induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles; induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles; increases degeneration of ovarian follicles and reduces testicular size in Japanese medaka (O. latipes)
Biotium OX40 / CD134/ TNFRSF4 (Immuno-Oncology Target)(OX40/3108), Biotin conjugate, 0.1mg/mL
ThisMAb recognizes a protein of 43 kDa, identified as OX40, which is also known as CD134. OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand/TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid cells. OX40 is upregulated at the sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low a
ABclonal Technology Cleaved Gasdermin DGly276
Gasdermin D is a member of the gasdermin family Members of this family appear to play a role in regulation of epithelial proliferation Gasdermin D has been suggested to act as a tumor suppressor Alternatively spliced transcript variants have been described
Cayman Chemical PhosphIn-bIotIn 5mg
A labeling reagent that selectively reacts with azido groups on modified proteins through the Staudinger ligation reaction; can be used in common avidin-based biochemical techniques in whole cells or by blotting experiments following SDS-PAGE; has been used successfully in conjunction with Daz-1 or Daz-2 to label and detect sulfenic acid sites in proteins
Cayman Chemical BIotIn-H10trIfluoroacetate 5mg
A biotinylated form of H10; has been used in ELISA and co-immunoprecipitation assays to assess AGR2 levels in cancer cells